Chemical Standard Operating Procedures (SOPs)

If you operate a chemical laboratory as defined in Washington Administrative Code 296-828, Hazardous Chemicals in Laboratories, you must have SOPs that describe the safety measures you require when using chemicals. Please see Section 6 of the UW Laboratory Safety Manual for more information about SOPs.

To assist you in writing SOPs, a blank SOP form (doc) and example SOPs are provided for you to use or to modify to your specific location and procedures and use. An SOP can address a single chemical, a group of similar chemicals, or a process. Any format of SOP is acceptable provided the minimum safety elements are addressed. The minimum safety elements are found on the following checklist: SOP Required Elements Checklist (doc). Below are links to example SOPs:

Chemical SOPs

Below are links to example SOPs and guidance documents which can be used to assist in the development of your site-specific SOP. Additional SOPs are available at the UCLA Standard Operating Procedure (SOP) Template Library.

Acrolein SOP (docx)
Acrylamide Use SOP (doc)
Anesthetic Gas SOP (pdf)
Benzene Use SOP (doc)
Biological Toxin Safe Work Practices (Guidance document)
Biological Toxin SOP (doc)
Bromodeoxyuridine (BrdU) SOP (doc)
Chemical Use Guidelines (pdf)
Chemotherapy and Other Hazardous Drugs SOP (doc)
Chemotherapy and Other Hazardous Drugs, Safe Use Guidelines (pdf)
Cyanides SOP (Customizable Document and Medical Guidelines)
Diphtheria Toxin SOP (doc)
Ethidium Bromide Use SOP (doc)
Flammable Solvents Use SOP (doc)
Formaldehyde Use SOP (doc)
Formaldehyde, Formalin, Paraformaldehyde, Safe Work Practices (Guidance document)
Gas Cylinder Use SOP (doc)
Hydrofluoric Acid SOP (doc)
Inorganic Acid Use SOP (doc)
Inorganic Base Use SOP (doc)
Lipopolysaccharide (LPS) SOP (doc)
Mercury Use SOP (doc)
MPTP SOP (doc)
MS-222 and Benzocaine (docx)
Nanomaterials (Guidance Document)
Oxidizer Use SOP (doc)
Perchloric Acid SOP (docx)
Peroxide-Former SOP (doc)
Phenol Use SOP (doc)

Process SOPs

This type of SOP is frequently used when a process is completely described from first step to last and activities such as fume hood use, varying PPE use, and waste neutralization are integrated into the steps. The example EH&S template SOP may not be useful for this type SOP except to cover items difficult to organize in a logical manner in the procedure, such as spill cleanup, perhaps.

Carbonate Removal SOP (doc)
Extractions Using Heavy Liquid SOP (doc)
High Temperature Furnace Use SOP (doc)
Sample Preparation Using Ethanol SOP (doc)
Solvent Distillation Process SOP (doc)

Questions and Support

For assistance with writing an SOP or if you would like to request that an SOP be added to this page, please contact EH&S at 206-616-3778 or